New TAVI device doesn’t require imaging or pacemaker
por Lauren Dubinsky, Senior Reporter | September 12, 2016
Cardiology
Population Health
Thousands of people with
rheumatic heart disease in
Africa will benefit
rheumatic heart disease in
Africa will benefit
A new transcatheter aortic valve implantation (TAVI) device that doesn’t require cardiovascular imaging or a pacemaker has the potential to save the lives of a large amount of rheumatic heart disease patients who need valve replacement. The research will be presented at the South Africa Heart Congress 2016.
There are about 15 million patients with rheumatic heart disease in Africa and 100,000 of them per year may need a heart valve intervention at some point. But the majority of those patients don’t have access to cardiac surgery or advanced cardiac imaging.
Right now, TAVI is only used for patients with calcific degenerative aortic valve disease, which is the most common aortic valve disease in developed countries. But rheumatic heart disease accounts for most of the patients who need a heart valve intervention in the developing countries.
The TAVI devices on the market require cardiac imaging to accurately position the new valve and a temporary pacemaker that makes the heart beat very fast so it stops blood from circulating to the rest of the body.
A team of researchers led by Dr. Jacques Sherman, lead author and cardiac surgeon at the University of Cape Town, South Africa, developed a TAVI device that doesn’t require rapid ventricular pacing to stop blood circulating to the body. It also doesn’t require cardiac imaging to position it.
The physicians use tactile feedback to place the device in the correct position, and it has a temporary backflow valve to stop the blood from leaking backward into the ventricle while the new valve is being implanted.
The researchers conducted a proof of concept study, which involved testing the device in a sheep model. They found that the device was easy to use, can be positioned correctly and that the procedure can be performed without rapid ventricular pacing.
With this new device, TAVI procedures can be done in hospitals without cardiac surgery at a fraction of the cost of conventional TAVI.
"Knowing from my own Pan-African collaborations how inadequate the provision of cardiac surgery is on the African continent this fascinating solution promises surgical help for all these young patients with rheumatic heart disease on a continent that has a fair density of general hospitals but hardly offers any open heart surgery,” Sherman said in a statement.
There are about 15 million patients with rheumatic heart disease in Africa and 100,000 of them per year may need a heart valve intervention at some point. But the majority of those patients don’t have access to cardiac surgery or advanced cardiac imaging.
Right now, TAVI is only used for patients with calcific degenerative aortic valve disease, which is the most common aortic valve disease in developed countries. But rheumatic heart disease accounts for most of the patients who need a heart valve intervention in the developing countries.
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A team of researchers led by Dr. Jacques Sherman, lead author and cardiac surgeon at the University of Cape Town, South Africa, developed a TAVI device that doesn’t require rapid ventricular pacing to stop blood circulating to the body. It also doesn’t require cardiac imaging to position it.
The physicians use tactile feedback to place the device in the correct position, and it has a temporary backflow valve to stop the blood from leaking backward into the ventricle while the new valve is being implanted.
The researchers conducted a proof of concept study, which involved testing the device in a sheep model. They found that the device was easy to use, can be positioned correctly and that the procedure can be performed without rapid ventricular pacing.
With this new device, TAVI procedures can be done in hospitals without cardiac surgery at a fraction of the cost of conventional TAVI.
"Knowing from my own Pan-African collaborations how inadequate the provision of cardiac surgery is on the African continent this fascinating solution promises surgical help for all these young patients with rheumatic heart disease on a continent that has a fair density of general hospitals but hardly offers any open heart surgery,” Sherman said in a statement.
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